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Genetic Modification and it’s Recent Effects on Medical Capabilities

Odessa Gelman
Apr 14, 2024
2 min read

Updated: Nov 4, 2024

In the ever-changing world of medicine, genetic modification is opening up compelling new possibilities. Recent breakthroughs in this field are changing the way we understand and treat diseases, like tailoring treatments to individual needs or developing precise therapies. Genetic modification is propelling medical capabilities to new heights.

“...genetic modification of humans via gene therapy is becoming a treatment option for diseases ranging from rare metabolic disorders to cancer. Coupling stem cell technology with recombinant DNA methods allows stem cells derived from a patient to be modified in the laboratory to introduce a desired gene.”

One significant advancement is in gene editing, particularly with the CRISPR-Cas9 technology. This tool enables scientists to make precise changes to DNA, offering hope for correcting genetic defects associated with various diseases like sickle cell anemia and cystic fibrosis. By addressing faulty genes at their core, these therapies offer possibilities for effective treatments.

In cancer research and treatment, genetic modification is also changing medical history. Scientists are using genetic engineering to create targeted therapies that focus on specific mutations driving cancer growth.

These treatments aim to attack cancer cells while sparing healthy tissue, potentially minimizing side effects and improving outcomes. Additionally, modified immune cells are being explored to bolster the body's natural defenses against cancer, showing promise in clinical trials.

Citations

“GMOs in Medicine and Research.” Encyclopædia Britannica, Encyclopædia Britannica,

inc., www.britannica.com/science/genetically-modified-organism/GMOs-in

medicine-and-research. Accessed 14 Apr. 2024.

Commissioner, Office of the. “FDA Approves First Gene Therapies to Treat Patients

with Sickle Cell Disease.” U.S. Food and Drug Administration, FDA,

www.fda.gov/news-events/press-announcements/fda-approves-first-gene

therapies-treat-patients-sickle-cell-disease. Accessed 14 Apr. 2024.

Cross, Deanna, and James K Burmester. “Gene Therapy for Cancer Treatment: Past,

Present and Future.” Clinical Medicine & Research, U.S. National Library of

Medicine, Sept. 2006,

www.ncbi.nlm.nih.gov/pmc/articles/PMC1570487/#:~:text=Gene%20transfer%20is%20a%20new,clinical%20trials%20with%20successful%20outcomes.






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